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Cat. No.: HY-126046

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ACP1b

ACP1b is an activator for ClpP protease with K_d of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 1371635-84-5
Formula: C₁₈H₁₈ClF₃N₂O₃S₂
Molecular Weight:466.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ACP1b Chemical Structure

CAS No.: 1371635-84-5

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ACP1b is an activator for ClpP protease with K_d of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL^[1].

Chemical Information

CAS No. 1371635-84-5
Molecular Weight 466.93
Formula C₁₈H₁₈ClF₃N₂O₃S₂
SMILES

CC(C)(C(NCCSC1=CC=CC=C1Cl)=O)S(=O)(C2=NC=C(C=C2)C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leung E, et al., Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chem Biol. 2011 Sep 23;18(9):1167-78. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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