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Cat. No.: HY-111283

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AJ-76

Name: AJ-76
Brand: MedChemExpress
SKU: HY-111283
Availability: PreOrder

(Synonyms: (+)-AJ 76; (1S,2R)-AJ 76)

AJ-76 ((+)-AJ 76; (1S,2R)-AJ 76) is a dopamine autoreceptor antagonist. AJ-76 can increase the synthesis and turnover of dopamine in the rat brain, while having little effect on the synthesis and turnover of serotonin (5-HT) and norepinephrine. AJ-76 can also antagonize the sedative effects of low-dose apomorphine and has a weak antagonistic effect on postsynaptic dopamine receptor.

For research use only. We do not sell to patients.

CAS No.: 85379-09-5
Formula: C₁₅H₂₃NO
Molecular Weight:233.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AJ-76 Chemical Structure

CAS No.: 85379-09-5

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Other In-stock Forms of AJ-76

AJ-76 hydrochloride

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 85379-09-5
Molecular Weight 233.35
Formula C₁₅H₂₃NO
SMILES

CCCN[C@H]1[C@@H](C)C2=C(C(OC)=CC=C2)CC1
Synonyms

(+)-AJ 76; (1S,2R)-AJ 76
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Svensson K, et al. (+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists. Naunyn Schmiedebergs Arch Pharmacol. 1986 Nov;334(3):234-45. [Content Brief]

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Topics Synaptic Plasticity & Brain Health
Synaptic plasticity is the activity-, experience-, development-, and injury-dependent modification of synaptic strength, number, and structure, and it remains a central mechanism for learning, memory, sensory adaptation, and brain health.

2026-06-18

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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