Aldafermin
Based on 1 Customer Validation
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH).
For research use only. We do not sell to patients.
- Purity: 97.63%
- CAS No.: 1616639-03-2
- Molecular Weight:21.06 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Aldafermin can inhibit bile acid synthesis and regulates metabolic homeostasis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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FGF19 (fibroblast growth factor 19)5-194
ELISA, FACS, Functional assay
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Immobilized Aldafermin can bind Anti-FGF-19 Antibody. The EC50 for this effect is 1.41 ng/mL.
Chemical Information
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CAS No. 1616639-03-2
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Appearance Liquid
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Molecular Weight 21.06 kDa
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Color Colorless to light yellow
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SMILES
[Aldafermin]
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Synonyms
NGM282
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)