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Referencia número: HY-180621

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Aldosterone hemiacetal

11 Cited Publications

Revisión del cliente

Based on 11 publication(s) in Google Scholar

Aldosterone hemiacetal is a nucleoside metabolite.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 6251-69-0
Fòrmula: C₂₁H₂₈O₅
Peso molecular:360.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (245 KB)

Aldosterone hemiacetal Chemical Structure

No. CAS: 6251-69-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Aldosterone hemiacetal is a nucleoside metabolite.

Chemical Information

No. CAS 6251-69-0
Peso molecular 360.44
Fòrmula C₂₁H₂₈O₅
SMILES

[H][C@]1(C(CO)=O)CC[C@]2([C@@]3(CCC4=CC(CC[C@@]4([C@]3([C@@H]5C[C@]12C(O5)O)[H])C)=O)[H])[H]
Structure Classification
- Steroids
Initial Source
- Endogenous metabolite
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (11)

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Science

Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency. [Abstract]

2026 Feb 5;391(6785):eadz4075. PMID: 41643022
Nat Chem Biol

Structures of the ADGRG2-Gs complex in apo and ligand-bound forms. [Abstract]

2022 Nov;18(11):1196-1203. PMID: 35982227
Acta Pharmacol Sin

Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays. [Abstract]

2022 Sep;43(9):2429-2438. PMID: 35110698

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2022 Sep;43(9):2429-2438. [Abstract]

For MR selectivity, cells were treated with 10 nM Aldosterone or indicated compounds and cultured for 16 h.
J Med Chem

Discovery of Novel Nonsteroidal SGRMs of Sulfonamide-2-Oxo-Tetrahydroquinoline Derivatives by Carbonyl Migration. [Abstract]

2026 Jan 22;69(2):1507-1529. PMID: 41490153
J Med Chem

Discovery and Optimization of N-Acyl-6-sulfonamide-tetrahydroquinoline Derivatives as Novel Non-Steroidal Selective Glucocorticoid Receptor Modulators. [Abstract]

2022 Dec 8;65(23):15710-15724. PMID: 36399795
Eur J Med Chem

Discovery of novel non-steroidal selective glucocorticoid receptor modulators by structure- and IGN-based virtual screening, structural optimization, and biological evaluation. [Abstract]

2022 Jul 5:237:114382. PMID: 35483323
Cell Signal

Inhibitory effects of Eplerenone on angiogenesis via modulating SGK1/TGF-β pathway in contralateral kidney of CKD pregnancy rats. [Abstract]

2024 Oct:122:111346. PMID: 39147296
Mol Cell Endocrinol

The mineralocorticoid receptor and its antagonist finerenone regulate hepatic lipid accumulation via the AMPK/SREBP1/FASN signaling. [Abstract]

2026 Oct:620:112845. PMID: 42264075
Int J Endocrinol

G Protein-Coupled Estrogen Receptor 1 (GPER1) Mediates Aldosterone-Induced Endothelial Inflammation in a Mineralocorticoid Receptor-Independent Manner. [Abstract]

2021 Jun 18:2021:5575927. PMID: 34239558

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Aldosterone (1 h). The level of cell culture medium IL-1β was detected.

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Aldosterone (1 h). ICAM-1 and VCAM-1 mRNA expressions were detected.

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Aldosterone (1 h). Western blot of IL-1β and NLRP-3 was detected.

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Aldosterone (1 h). The protein level of IL-1β from PBS to 10^-9 M G15 was detected.
Int Urol Nephrol

Aldosterone promotes calcification of vascular smooth muscle cells in mice through the AIF-1/Wnt/β-catenin signaling pathway. [Abstract]

2025 Feb;57(2):613-623. PMID: 39312016
Gene Rep

2025 Oct 4.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (245 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

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Keywords

Aldosterone hemiacetal

11 Cited Publications

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Actividad biológica
- Descripciòn
Chemical Information
Publications (11)
Pureza y Documentación

1/16
1/16

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2022 Sep;43(9):2429-2438. [Abstract]

Customer Validation
For MR selectivity, cells were treated with 10 nM Aldosterone or indicated compounds and cultured for 16 h.
1/16

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Customer Validation
Aldosterone (1 h). The level of cell culture medium IL-1β was detected.
1/16

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Customer Validation
Aldosterone (1 h). ICAM-1 and VCAM-1 mRNA expressions were detected.
1/16

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Customer Validation
Aldosterone (1 h). Western blot of IL-1β and NLRP-3 was detected.
1/16

Aldosterone hemiacetal purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2021 Jun 18:2021:5575927. [Abstract]

Customer Validation
Aldosterone (1 h). The protein level of IL-1β from PBS to 10^-9 M G15 was detected.

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Aldosterone hemiacetal

Publications Citing Use of MedChemExpress (MCE) Aldosterone hemiacetal

Actividad biológica

Chemical Information

Publications (11)

Pureza y Documentación

Calculators

Help & FAQs

Aldosterone hemiacetal

Publications Citing Use of MedChemExpress (MCE) Aldosterone hemiacetal

Actividad biológica

Chemical Information

Publications (11)

Pureza y Documentación

Calculators

Help & FAQs

Aldosterone hemiacetal Related Classifications

HY-180621 Related Classifications