Alpha-tocopheryloxyacetic acid
Alpha-tocopheryloxyacetic acid (alpha-TEA) is an inducer of cancer cell apoptosis pathway. Alpha-tocopheryloxyacetic acid is promising for research of solid and hematological malignancies.
For research use only. We do not sell to patients.
- CAS No.: 261929-52-6
- Formula: C31H52O4
- Molecular Weight:488.74
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | EC50 |
51 μM
Compound: alpha-TEA
|
Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis
Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis
|
[PMID: 23092906] |
| MDA-MB-231 | EC50 |
35 μM
Compound: alpha-TEA
|
Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis
Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis
|
[PMID: 23092906] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 261929-52-6
-
Molecular Weight 488.74
-
Formula C31H52O4
-
SMILES
O=C(O)COC1=C(C)C(C)=C2C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C1C
-
Synonyms
alpha-TEA
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)