Ambroxol hydrochloride solution
Ambroxol hydrochloride solution is mainly composed of Ambroxol hydrochloride (HY-B1039A). Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research.
For research use only. We do not sell to patients.
- CAS No.: 23828-92-4
- Formula: C13H19Br2ClN2O
- Molecular Weight:414.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 23828-92-4
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Molecular Weight 414.56
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Formula C13H19Br2ClN2O
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SMILES
O[C@H]1CC[C@@H](CC1)NCC2=CC(Br)=CC(Br)=C2N.[H]Cl
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Synonyms
NA-872 hydrochloride solution
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Vojo Deretic, et al. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert Opin Drug Metab Toxicol. 2019 Mar;15(3):213-218. [Content Brief]
[2]. Anna Migdalska-Richards, et al. Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice. Ann Neurol. 2016 Nov;80(5):766-775. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ambroxol hydrochloride solution Related Classifications
HY-FLB1039A Related Classifications
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