Amino-PEG24-Boc
Based on 1 Customer Validation
Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 2170987-96-7
- Formula: C55H111NO26
- Molecular Weight:1202.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2170987-96-7
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Appearance Solid
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Molecular Weight 1202.46
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Formula C55H111NO26
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Color White to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 116.67 mg/mL (97.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8316 mL | 4.1581 mL | 8.3163 mL | 20.7907 mL |
| 5 mM | 0.1663 mL | 0.8316 mL | 1.6633 mL | 4.1581 mL | |
| 10 mM | 0.0832 mL | 0.4158 mL | 0.8316 mL | 2.0791 mL | |
| 15 mM | 0.0554 mL | 0.2772 mL | 0.5544 mL | 1.3860 mL | |
| 20 mM | 0.0416 mL | 0.2079 mL | 0.4158 mL | 1.0395 mL | |
| 25 mM | 0.0333 mL | 0.1663 mL | 0.3327 mL | 0.8316 mL | |
| 30 mM | 0.0277 mL | 0.1386 mL | 0.2772 mL | 0.6930 mL | |
| 40 mM | 0.0208 mL | 0.1040 mL | 0.2079 mL | 0.5198 mL | |
| 50 mM | 0.0166 mL | 0.0832 mL | 0.1663 mL | 0.4158 mL | |
| 60 mM | 0.0139 mL | 0.0693 mL | 0.1386 mL | 0.3465 mL | |
| 80 mM | 0.0104 mL | 0.0520 mL | 0.1040 mL | 0.2599 mL |
Amino-PEG24-Boc Related Classifications
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