Anti-Mouse CD209b Antibody (22D1)
Based on 1 Customer Validation
Anti-Mouse CD209b Antibody (22D1) is an anti-mouse CD209b IgG1 antibody inhibitor derived from the host Armenian Hamster. Anti-Mouse CD209b Antibody (22D1) can block SIGN-R1. Anti-Mouse CD209b Antibody (22D1) can be used for the researches of infection, inflammation and immunology, such as toxoplasma infection and pneumonia.
For research use only. We do not sell to patients.
- Purity: 99.00%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Parasite Isoforms
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Biological Activity
Armenian Hamster IgG
Mouse
CD209b
Anti-Mouse CD209b Antibody (22D1) (5 μg, 30 mins) completely abolishes the uptake of the polysaccharide CPS14 of S. pneumoniae in microglia cells[2].
Anti-Mouse CD209b Antibody (22D1) (60 mins) blocks pullulan nanogel binding to SIGN-R1 in HeLa cells[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anti-Mouse CD209b Antibody (22D1) (subcutaneously injection, 60 mins prior to the injection of PNG) blocks pullulan nanogel (PNG) engulfed by medullary macrophages in the draining lymph node[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
69165 [NCBI]
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
in vivo SIGN-R1 blockade; Immunohistochemistry (frozen); Western blot; Flow cytometry
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-Mouse CD209b Antibody (22D1)]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (260 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Njiri OA, et al. CD209 C-Type Lectins Promote Host Invasion, Dissemination, and Infection of Toxoplasma gondii. Front Immunol. 2020 Apr 23;11:656. [Content Brief]
[2]. Park JY, et al. The C-type lectin CD209b is expressed on microglia and it mediates the uptake of capsular polysaccharides of Streptococcus pneumoniae. Neurosci Lett. 2009 Feb 6;450(3):246-51. [Content Brief]
[3]. Muraoka D, et al. Low-frequency CD8+T cells induced by SIGN-R1+ macrophage-targeted vaccine confer SARS-CoV-2 clearance in mice. NPJ Vaccines. 2024 Sep 18;9(1):173. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse CD209b Antibody (22D1) Related Classifications
HY-P99122 Related Classifications
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