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Cat. No.: HY-155301

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Antileishmanial agent-24

Antileishmanial agent-24 (compound 33) is an antileishmanial agent with an IC₅₀ of 5.39 μM against amastigote.

For research use only. We do not sell to patients.

CAS No.: 2999670-36-7
Formula: C₃₄H₂₉Cl₄N₃O₂
Molecular Weight:653.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Antileishmanial agent-24 Chemical Structure

CAS No.: 2999670-36-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
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Bioz

Biological Activity

Description

Antileishmanial agent-24 (compound 33) is an antileishmanial agent with an IC₅₀ of 5.39 μM against amastigote^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
J774.A1	CC₅₀	63.5 μM Compound: 33	Cytotoxicity against mouse J774.A1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against mouse J774.A1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 37837672]

Chemical Information

CAS No. 2999670-36-7
Molecular Weight 653.42
Formula C₃₄H₂₉Cl₄N₃O₂
SMILES

ClC1=CC=C(N=C(C2=CC=C(OCC(O)CN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)C=C2)C=C5C6=CC=CC=C6Cl)C5=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sarita Katiyar, et al. Design, synthesis, and biological evaluation of quinoline-piperazine/pyrrolidine derivatives as possible antileishmanial agents. Eur J Med Chem. 2023 Oct 7:261:115863. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Antileishmanial agent-24

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Antileishmanial agent-24 Related Classifications

HY-155301 Related Classifications