Antiproliferative agent-27
Antiproliferative agent-27 (compound 11) is an antiproliferative agent that significantly reduces the number of tumor cell colonies and induces apoptosis. Antiproliferative agent-27 has the potential to be used in the study of cancer.
For research use only. We do not sell to patients.
- Formula: C26H40FNO6S
- Molecular Weight:513.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
4.3 μM
Compound: 13
|
Growth inhibition of human A549 cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human A549 cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
| HBL-100 | GI50 |
4.2 μM
Compound: 13
|
Growth inhibition of human HBL-100 cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human HBL-100 cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
| HeLa | GI50 |
3.3 μM
Compound: 13
|
Growth inhibition of human HeLa cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human HeLa cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
| SW1573 | GI50 |
4.2 μM
Compound: 13
|
Growth inhibition of human SW1573 cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human SW1573 cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
| T47D | GI50 |
9.7 μM
Compound: 13
|
Growth inhibition of human T47D cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human T47D cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
| WiDr | GI50 |
3.6 μM
Compound: 13
|
Growth inhibition of human WiDr cells measured after 48 hrs by SRB colorimetric assay
Growth inhibition of human WiDr cells measured after 48 hrs by SRB colorimetric assay
|
[PMID: 37137247] |
Chemical Information
-
Molecular Weight 513.66
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Formula C26H40FNO6S
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SMILES
O[C@H]1[C@H](OCC2=CC=CC=C2)[C@@H](F)[C@@H](S(=O)(CCCCCCCCCCCC)=O)N3[C@@H]1COC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)