Antiproliferative agent-43
Antiproliferative agent-43 (Compound e4 ) has notable cytotoxic effects against cancer cell lines and causes apoptosis by stopping the cell cycle at G1 phase.
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- CAS 番号: 3034239-44-3
- 分子式: C45H57NO6S2
- 分子量:772.07
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
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- 純度とドキュメンテーション
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生物活性
製品説明
体外実験
Antiproliferative agent-43 (0, 1.23, 2.45, 2.90 μM, 48 h) induces G1 phase cell cycle arrest in K562 cells, accompanied by abnormal nuclear morphology [1].
Antiproliferative agent-43 (0, 1.23, 2.45 , 2.90 μM, 48 h) apoptosis induces by mitochondrial pathway in K562 cells [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:K562
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Concentration:0, 1.23, 2.45 , 2.90 μM
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Incubation Time:48h
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Result:Induced G1 phase cell cycle arrest in the K562 cell line.
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Cell Line:K562
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Concentration:0, 1.23, 2.45 , 2.90 μM
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Incubation Time:48h
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Result:The apoptotic cells induced by antiproliferative agent-43 increased from 6.35% in the negative control to 13.36, 37.99, and 64.94%, with a concentration-dependent manner.
化学情報
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CAS 番号 3034239-44-3
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分子量 772.07
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分子式 C45H57NO6S2
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SMILES
COC1=CC=C(C[C@H](N(CC2)C)[C@](C=C3OC)([H])[C@@]42CC3=O)C4=C1OCCCCOC(CCCCC(SCC5=CC=CC=C5)CCSCC6=CC=CC=C6)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antiproliferative agent-43 関連分類
HY-155413 関連分類
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