Antitumor agent-149
Antitumor agent-149 (Compound 3) is an analogue of Echinomycin (HY-106101). Antitumor agent-149 inhibits HIF-1α-mediated transcription. Antitumor agent-149 induces cancer cell apoptosis. Antitumor agent-149 inhibits tumor growth in SW620 xenograft mice model.
For research use only. We do not sell to patients.
- CAS No.: 2368983-54-2
- Formula: C52H64N10O14S
- Molecular Weight:1085.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antitumor agent-149 shows cytotoxicity against SW620 and MIA PaCa-2 cells with IC50s of 0.85 nM and 1.4 nM respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2368983-54-2
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Molecular Weight 1085.19
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Formula C52H64N10O14S
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SMILES
O=C(N[C@@H](C(N[C@H](C(N([C@@H](CSC1)C(N([C@H]2C(C)C)C)=O)C)=O)C)=O)COC([C@H](C(C)C)N(C([C@H]1N(C([C@H](C)NC([C@H](NC(C3=NC(C=CC=C4)=C4C=C3O)=O)COC2=O)=O)=O)C)=O)C)=O)C5=NC(C=CC=C6)=C6C=C5O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-149 Related Classifications
HY-161425 Related Classifications
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