Antitumor agent-162
Antitumor agent-162 (compound 52a) is a potent and orally active antitumor agent. Antitumor agent-162 shows cytotoxicity.
For research use only. We do not sell to patients.
- Formula: C26H19Cl2NO4
- Molecular Weight:480.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antitumor agent-162 (compound 52a) (0-5000 nM) shows cytotoxicity with IC50s of 63, 84 nM for Mut6, UTSW63 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| route | T1/2 (h) | Cmax (ng/mL) | Tmax (h) | AUClast (ng*min/mL) | CL | kp (AUCbrain/AUCplasma) | |
| plasma | i.p. (10 mg/kg) | 234 | 1303 | 30 | 289860 | 0.13 | - |
| i.v. (5 mg/kg) | 189 | 12000 | 5 | 885630 | 0.14 | - | |
| p.o. (20 mg/kg) | 208 | 3404 | 30 | 1387613 | 0.14 | - | |
| brain | i.p. (10 mg/kg) | 182 | 2526 | 90 | 720503 | - | 2.49 |
| i.v. (5 mg/kg) | 294 | 3257 | 5 | 767638 | - | 0.87 | |
| p.o. (20 mg/kg) | 254 | 2381 | 90 | 1774789 | - | 1.28 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 480.34
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Formula C26H19Cl2NO4
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SMILES
ClC1=CC(Cl)=CC(C(COC2=CC=C(C=C2)N3C(C4C(C5C6CC6C57C=CC47)C3=O)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-162 Related Classifications
HY-162560 Related Classifications
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