Apocholic acid

Cat. No.: HY-W747583 Purity: 99.49%: Data Sheet
COA

SDS
Handling Instructions
FAQs
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Apocholic acid is a bile acid belonging to steroidal organic acids. Apocholic acid is an endogenous metabolite.

For research use only. We do not sell to patients.

Apocholic acid Chemical Structure

CAS No. : 641-81-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Human Endogenous Metabolite Microbial Metabolite

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Description

Apocholic acid is a bile acid belonging to steroidal organic acids. Apocholic acid is an endogenous metabolite^[1].

In Vivo

Apocholic acid is an endogenous metabolite^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

390.56

Formula

C₂₄H₃₈O₄

CAS No.

641-81-6

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12C(CC[C@]2([H])[C@H](C)CCC(O)=O)=C3[C@@](C[C@@H]1O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C

Structure Classification

Steroids

Initial Source

Endogenous metabolite

human urine

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (128.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5604 mL	12.8021 mL	25.6043 mL
5 mM	0.5121 mL	2.5604 mL	5.1209 mL
10 mM	0.2560 mL	1.2802 mL	2.5604 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.49%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (249 KB) HNMR (456 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. He L, et al. Metabolic Profiling of Bile Acids in the Urine of Patients with Alcohol-Associated Liver Disease. Hepatol Commun. 2021 Jan 20;5(5):798-811. [Content Brief]

[2]. LACASSAGNE A, et al. Carcinogenic activity of apocholic acid. Nature. 1961 Jun 10;190:1007-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5604 mL	12.8021 mL	25.6043 mL	64.0107 mL
	5 mM	0.5121 mL	2.5604 mL	5.1209 mL	12.8021 mL
	10 mM	0.2560 mL	1.2802 mL	2.5604 mL	6.4011 mL
	15 mM	0.1707 mL	0.8535 mL	1.7070 mL	4.2674 mL
	20 mM	0.1280 mL	0.6401 mL	1.2802 mL	3.2005 mL
	25 mM	0.1024 mL	0.5121 mL	1.0242 mL	2.5604 mL
	30 mM	0.0853 mL	0.4267 mL	0.8535 mL	2.1337 mL
	40 mM	0.0640 mL	0.3201 mL	0.6401 mL	1.6003 mL
	50 mM	0.0512 mL	0.2560 mL	0.5121 mL	1.2802 mL
	60 mM	0.0427 mL	0.2134 mL	0.4267 mL	1.0668 mL
	80 mM	0.0320 mL	0.1600 mL	0.3201 mL	0.8001 mL
	100 mM	0.0256 mL	0.1280 mL	0.2560 mL	0.6401 mL

Apocholic acid Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apocholic acid641-81-6Endogenous Metabolitebile acidsteroidal organic acidsendogenous metaboliteInhibitorinhibitorinhibit

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Apocholic acid

Apocholic acid Related Antibodies

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