641-81-6
Chemical Structure
Apocholic acid
- CAS 番号: 641-81-6
- Formula:C24H38O4
- Molecular Weight:390.56
IUPAC Name: (R)-4-((3R,5R,9R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,9,10,11,12,13,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: XWJTYEGVQBFZHI-IMPNNSMHSA-N
SMILES: C[C@@]12C(CC[C@]2([H])[C@H](C)CCC(O)=O)=C3[C@@](C[C@@H]1O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
Biological Activity: Apocholic acid is a bile acid belonging to steroidal organic acids. Apocholic acid is an endogenous metabolite[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Apocholic acid | 98.79% | Apocholic acid is a bile acid belonging to steroidal organic acids. Apocholic acid is an endogenous metabolite. | ||||||||||||||||||||
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Ursodeoxycholic acid (Standard) | 99.83% | Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active. | ||||||||||||||||||||
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Allochenodeoxycholic acid | 99.94% | Allochenodeoxycholic acid is a nucleoside metabolite. | ||||||||||||||||||||
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3α,12β-Dihydroxycholanoic acid (Standard) | ≥98% | 3α,12β-Dihydroxycholanoic acid (Standard) is the analytical standard of 3α,12β-Dihydroxycholanoic acid (HY-43470). This product is intended for research and analytical applications. 3α,12β-Dihydroxycholanoic acid is a dihydroxy bile acid that is detectable in healthy urine samples. 3α,12β-Dihydroxycholanoic acid carries hydroxy substituents at the 3α and 12β positions of the 5β-cholanoic acid steroid skeleton. | ||||||||||||||||||||
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Cholic acid impurity 1 | 95.05% | Cholic acid impurity 1 is an impurity of Cholic acid (HY-N0324). | ||||||||||||||||||||
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3-Epideoxycholic acid | 99.90% | 3-Epideoxycholic acid is a secondary bile acid and a microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR in dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exerts anti-inflammatory activity. 3-Epideoxycholic acid can promote the growth of the bacterium Bacteroides. 3-Epideoxycholic acid can be used in research related to inflammatory and immune diseases as well as bacterial infections. | ||||||||||||||||||||
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Deoxycholic acid | 99.94% | Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5. | ||||||||||||||||||||
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Deoxycholic acid-13C | 98.0% | Deoxycholic acid-13C is the 13C-labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. | ||||||||||||||||||||
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α-Ergostenol | 99.97% | α-Ergostenol (Ergost-8(14)-en-3-ol) is a phytosterol isolated from the fruits of Cirsium palustre and C. rivulare. | ||||||||||||||||||||
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Apocholic Acid (Delta 14 isomer) | Apocholic Acid (Delta 14 isomer) is a cholic acid. | |||||||||||||||||||||
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Allodeoxycholic acid | Allodeoxycholic acid is a nucleoside metabolite. | |||||||||||||||||||||
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