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  5. Euchresta horsfieldii (Lesch.) J. Benn.
  6. ArnicolideC

ArnicolideC is a sesquiterpene lactone isolated Centipeda minima. ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation.

For research use only. We do not sell to patients.

ArnicolideC Chemical Structure

ArnicolideC Chemical Structure

CAS No. : 34532-67-7

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Description

ArnicolideC is a sesquiterpene lactone isolated Centipeda minima[1]. ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation[2].

Molecular Weight

334.41

Formula

C19H26O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)C(O[C@H]1[C@@]([C@@H]2C)([H])[C@@](OC2=O)([H])C[C@@H](C)[C@@]3([H])[C@]1(C(C=C3)=O)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (299.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9903 mL 14.9517 mL 29.9034 mL
5 mM 0.5981 mL 2.9903 mL 5.9807 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.77%

COA (266 KB) RP-HPLC (335 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9903 mL 14.9517 mL 29.9034 mL 74.7585 mL
5 mM 0.5981 mL 2.9903 mL 5.9807 mL 14.9517 mL
10 mM 0.2990 mL 1.4952 mL 2.9903 mL 7.4759 mL
15 mM 0.1994 mL 0.9968 mL 1.9936 mL 4.9839 mL
20 mM 0.1495 mL 0.7476 mL 1.4952 mL 3.7379 mL
25 mM 0.1196 mL 0.5981 mL 1.1961 mL 2.9903 mL
30 mM 0.0997 mL 0.4984 mL 0.9968 mL 2.4920 mL
40 mM 0.0748 mL 0.3738 mL 0.7476 mL 1.8690 mL
50 mM 0.0598 mL 0.2990 mL 0.5981 mL 1.4952 mL
60 mM 0.0498 mL 0.2492 mL 0.4984 mL 1.2460 mL
80 mM 0.0374 mL 0.1869 mL 0.3738 mL 0.9345 mL
100 mM 0.0299 mL 0.1495 mL 0.2990 mL 0.7476 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ArnicolideC34532-67-7OthersInhibitorinhibitorinhibit

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