MB-07803
MB-07803 is an orally active second-generation prodrug inhibitor of fructose-1,6-bisphosphatase (FBP1). MB-07803 directly inhibits the rate-limiting enzyme in gluconeogenesis. MB-07803 regulates blood glucose and is used in studies of type 2 diabetes.
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- CAS. Nr.: 882757-24-6
- Formel: C24H37N4O7PS
- Molecular Weight:556.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
31, 121, 189 nM for human, monkey, and rat, respectively [1] .
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 882757-24-6
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Molecular Weight 556.61
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Formel C24H37N4O7PS
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SMILES
O=C(C(C)(C)NP(NC(C)(C)C(OCC)=O)(C1=CC=C(C2=C(C(C(C)(C)C)=O)SC(N)=N2)O1)=O)OCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)