PD-159020
PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively.
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- CAS. Nr.: 177904-00-6
- Formel: C32H25NO8
- Molecular Weight:551.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
IC50: 30 nM (hETA), 50 nM (hETB)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | IC50 |
0.05 μM
Compound: 37
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Inhibitory concentration against Endothelin B receptor expressed in CHO-K1 cells
Inhibitory concentration against Endothelin B receptor expressed in CHO-K1 cells
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10.1016/0960-894X(96)00170-9 |
PD-159020 demonstrates excellent inhibition of arachidonic acid release, AAR-B, with an IC50 of 0.23 μM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 177904-00-6
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Molecular Weight 551.54
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Formel C32H25NO8
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SMILES
O=C(C(N1CC2=CC=C(OCO3)C3=C2)=C(C4=CC=C(OCO5)C5=C4)C6=C1C=C(OCC7=CC=CC=C7)C(OC)=C6)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PD-159020 Related Classifications
HY-101598 Related Classifications
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