country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-187838S

Copy Link Print Information

Adonertinib

Name: Adonertinib
Brand: MedChemExpress
SKU: HY-187838S
Availability: PreOrder

(Synonyms: FHND9041)

Adonertinib (FHND9041) is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, which is applicable to research related to advanced non-small cell lung cancer carrying EGFR-sensitive mutations.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2211116-92-4
Formel: C₃₀H₃₂D₃N₇O₂
Molecular Weight:528.66

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Adonertinib Chemical Structure

CAS. Nr.: 2211116-92-4

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle EGFR Isoform-spezifische Produkte anzeigen :

In Vitro

Adonertinib (FHND9041) covalently binds to mutant EGFR and exhibits low inhibitory activity against wild-type EGFR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Adonertinib (FHND9041) exhibits superior progression-free survival benefits and a lower incidence of adverse events in advanced NSCLC harboring sensitive EGFR mutations, particularly the EGFR Ex19del mutation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 2211116-92-4
Unlabeled CAS 1825287-91-9
Molecular Weight 528.66
Formel C₃₀H₃₂D₃N₇O₂
SMILES

COC(C=C(C(NC(C=C)=O)=C1)N(C)CCN(C)C([2H])([2H])[2H])=C1NC2=NC=CC(C(C3=CC=C4)=CN5C3=C4CCC5)=N2
Synonyms

FHND9041
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Shi Y K, et al. Adonertinib (FHND9041) versus Afatinib as First‑line Treatment for Advanced Non‑small‑cell Lung Cancer with EGFR Sensitive Mutation (FHND9041‑III‑01): A Multi‑centre, Open‑label, Randomised Phase 3 Trial. 2026.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen