Api137
Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain.
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- CAS. Nr.: 1428789-03-0
- Formel: C104H171N37O22
- Molecular Weight:2291.71
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 1428789-03-0
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Molecular Weight 2291.71
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Formel C104H171N37O22
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Sequence
N,N,N’,N’-Tetramethylguanidino-{Orn}-Asn-Asn-Arg-Pro-Val-Tyr-Ile-Pro-Arg-Pro-Arg-Pro-Pro-His-Pro-Arg-Leu
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Sequence Shortening
N,N,N’,N’-Tetramethylguanidino-{Orn}-NNRPVYIPRPRPPHPRL
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Florin T, et, al. An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. Nat Struct Mol Biol. 2017 Sep;24(9):752-757. [Content Brief]
[2]. Graf M, et, al. Intracellular Antimicrobial Peptides Targeting the Protein Synthesis Machinery. Adv Exp Med Biol. 2019:1117:73-89. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)