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Aprinocarsen sodium

(Synonyms: ISIS 3521 sodium)
1 Cited Publications
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Aprinocarsen (ISIS 3521) sodium, a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α). Aprinocarsen sodium is a 20-mer oligonucleotide, it regulates cell differentiation and proliferation. Aprinocarsen sodium inhibits the growth of human tumor cell lines in nude mice. Aprinocarsen sodium shows the value as a chemotherapeutic compound of human cancers.

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  • Reinheit : 98.42%
  • CAS. Nr.: 331257-53-5
  • Formel: C196H230N68Na19O105P19S19
  • Molecular Weight:6435.2 (free acid)
  • Speicherung:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Aprinocarsen sodium Chemical Structure
    Aprinocarsen sodium Chemical Structure
CAS. Nr.: 331257-53-5
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  • Aprinocarsen sodium Chemical Structure
    Aprinocarsen sodium Chemical Structure DNA, d(P-thio)(G-T-T-C-T-C-G-C-T-G-G-T-G-A-G-T-T-T-C-A), sodium salt (1:19)
    1/16
  • DNA, d(P-thio)(G-T-T-C-T-C-G-C-T-G-G-T-G-A-G-T-T-T-C-A), sodium salt (1:19)