Asebogenin
Asebogenin has antimalarial activity in vitro. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps.
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- CAS. Nr.: 520-42-3
- Formel: C16H16O5
- Molecular Weight:288.30
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KB | ED50 |
>10 μg/mL
Compound: 2, Asebogenin
|
Cytotoxicity against human KB cells after 72 hrs
Cytotoxicity against human KB cells after 72 hrs
|
[PMID: 8158163] |
Chemical Information
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CAS. Nr. 520-42-3
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Molecular Weight 288.30
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Formel C16H16O5
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SMILES
O=C(C1=C(O)C=C(OC)C=C1O)CCC2=CC=C(O)C=C2
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. [Content Brief]
[2]. Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)