AY254
AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling
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- CAS. Nr.: 2093408-03-6
- Formel: C30H49N9O6
- Molecular Weight:631.77
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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PAR2 2 nM (EC50) |
Chemical Information
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CAS. Nr. 2093408-03-6
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Molecular Weight 631.77
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Formel C30H49N9O6
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Sequence
{5-Isoxazolylcarbonyl-Cha}-{Chg}-Ala-Arg-NH2
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Sequence Shortening
{5-Isoxazolylcarbonyl-Cha}-{Chg}-AR-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)