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Art. -Nr.: HY-143465

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BChE-IN-5

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC₅₀ of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease.

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CAS. Nr.: 2983586-25-8
Formel: C₃₀H₄₂N₄O
Molecular Weight:474.68

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

BChE-IN-5 Chemical Structure

CAS. Nr.: 2983586-25-8

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Preis

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Menge

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC₅₀ of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease^[1].

IC₅₀ & Target

AChE

BChE

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

In Vitro

BChE-IN-5 (compound 18) shows inhibitory potencies for hBChE and hAChE with IC₅₀s of 2.8 nM, 16000 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2983586-25-8
Molecular Weight 474.68
Formel C₃₀H₄₂N₄O
SMILES

O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Meden A, et al. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112766. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Art. -Nr.:
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BChE-IN-5

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen