Br-C10-methyl ester
Based on 1 Customer Validation
Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein.
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- Reinheit : 97.87%
- CAS. Nr.: 6287-90-7
- Formel: C12H23BrO2
- Molecular Weight:279.21
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Alkyl/ether |
Chemical Information
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CAS. Nr. 6287-90-7
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Appearance <12.5°C Solid,>12.5°C Liquid
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Molecular Weight 279.21
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Formel C12H23BrO2
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Color Colorless to light yellow
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SMILES
O=C(OC)CCCCCCCCCCBr
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (358.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5815 mL | 17.9077 mL | 35.8153 mL | 89.5383 mL |
| 5 mM | 0.7163 mL | 3.5815 mL | 7.1631 mL | 17.9077 mL | |
| 10 mM | 0.3582 mL | 1.7908 mL | 3.5815 mL | 8.9538 mL | |
| 15 mM | 0.2388 mL | 1.1938 mL | 2.3877 mL | 5.9692 mL | |
| 20 mM | 0.1791 mL | 0.8954 mL | 1.7908 mL | 4.4769 mL | |
| 25 mM | 0.1433 mL | 0.7163 mL | 1.4326 mL | 3.5815 mL | |
| 30 mM | 0.1194 mL | 0.5969 mL | 1.1938 mL | 2.9846 mL | |
| 40 mM | 0.0895 mL | 0.4477 mL | 0.8954 mL | 2.2385 mL | |
| 50 mM | 0.0716 mL | 0.3582 mL | 0.7163 mL | 1.7908 mL | |
| 60 mM | 0.0597 mL | 0.2985 mL | 0.5969 mL | 1.4923 mL | |
| 80 mM | 0.0448 mL | 0.2238 mL | 0.4477 mL | 1.1192 mL | |
| 100 mM | 0.0358 mL | 0.1791 mL | 0.3582 mL | 0.8954 mL |
Br-C10-methyl ester Related Classifications
HY-130641 Related Classifications
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