CTL-12
CTL-12 is an inhibitor of fatty acid synthase (FASN) (IC50: 2.5 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H21ClN4O4
- Molecular Weight:440.88
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
IC50: 2.5 μM (FASN)[1]
Chemical Information
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Molecular Weight 440.88
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Formel C22H21ClN4O4
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SMILES
O=C(C1=CC=C2C(N=C(C3=C(O)C=CC(Cl)=C3)N2)=C1)N4CCN(C(C5(O)CC5)=O)CC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CTL-12 Related Classifications
HY-149541 Related Classifications
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