DCOIT (Standard)
DCOIT (Standard) (Kathon 930 (Standard)) is the analytical standard of DCOIT (HY-W041308). This product is intended for research and analytical applications. DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology.
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- Reinheit: 98%
- CAS. Nr.: 64359-81-5
- Formel: C11H17Cl2NOS
- Molecular Weight:282.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 64359-81-5
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Molecular Weight 282.23
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Formel C11H17Cl2NOS
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SMILES
O=C1N(CCCCCCCC)SC(Cl)=C1Cl
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Synonyms
Kathon 930 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Keywords
- DCOIT (Standard)
- 64359-81-5
- Kathon 930 (Standard)
- Reference Standards
- Environmental Pollutants
- GnRH Receptor
- H295R cells
- hypothalamus-pituitary-gonadal axis
- Gαi
- isothiazolinone biocide
- blood-brain barrier permeability
- mitochondrial calcium uniporter
- reproductive endocrine disruption
- marine medaka
- MAPK pathway
- O. melastigma
- Inhibitor
- inhibitor
- inhibit