G247
G247 is a specific MsbA inhibitor. G247 acts as a transmembrane domains (TMDs) wedge, symmetrically increasing nucleotide-binding domains (NBDs) separation and preventing conformational transition of MsbA. G247 suppresses ATPase activity by increasing inter-NBD distance.
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- Formel: C24H19Cl2FO3
- Molecular Weight:445.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
MsbA[1]
Chemical Information
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Molecular Weight 445.31
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Formel C24H19Cl2FO3
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SMILES
C[C@@H](C1=C(C=CC(F)=C1Cl)Cl)OC2=CC3=C(C=CC(/C=C/C(O)=O)=C3C4CC4)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)