Hydroxy-PEG1-(CH2)2-Boc
Based on 1 Customer Validation
Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 99.96%
- CAS. Nr.: 671802-00-9
- Formel: C9H18O4
- Molecular Weight:190.24
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 671802-00-9
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Appearance Liquid (Density: 1.031±0.06 g/cm3)
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Molecular Weight 190.24
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Formel C9H18O4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
H2O : 100 mg/mL (525.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (525.65 mM); Clear solution; Need ultrasonic
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2565 mL | 26.2826 mL | 52.5652 mL | 131.4129 mL |
| 5 mM | 1.0513 mL | 5.2565 mL | 10.5130 mL | 26.2826 mL | |
| 10 mM | 0.5257 mL | 2.6283 mL | 5.2565 mL | 13.1413 mL | |
| 15 mM | 0.3504 mL | 1.7522 mL | 3.5043 mL | 8.7609 mL | |
| 20 mM | 0.2628 mL | 1.3141 mL | 2.6283 mL | 6.5706 mL | |
| 25 mM | 0.2103 mL | 1.0513 mL | 2.1026 mL | 5.2565 mL | |
| 30 mM | 0.1752 mL | 0.8761 mL | 1.7522 mL | 4.3804 mL | |
| 40 mM | 0.1314 mL | 0.6571 mL | 1.3141 mL | 3.2853 mL | |
| 50 mM | 0.1051 mL | 0.5257 mL | 1.0513 mL | 2.6283 mL | |
| 60 mM | 0.0876 mL | 0.4380 mL | 0.8761 mL | 2.1902 mL | |
| 80 mM | 0.0657 mL | 0.3285 mL | 0.6571 mL | 1.6427 mL | |
| 100 mM | 0.0526 mL | 0.2628 mL | 0.5257 mL | 1.3141 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Hydroxy-PEG1-(CH2)2-Boc Related Classifications
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