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Art. -Nr.: HY-119325

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Lanperisone

(Synonyms: NK433 free base)

Lanperisone is a novel oral muscle relaxant with anticancer activity. Lanperisone produces non-apoptotic cell death by inhibiting monosynaptic and polysynaptic reflex potentials. Lanperisone is also believed to play an important role in the dysregulation of iron metabolism and antioxidant systems to modulate processes associated with ischemic stroke.

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CAS. Nr.: 116287-14-0
Formel: C₁₅H₁₈F₃NO
Molecular Weight:285.30

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Lanperisone Chemical Structure

CAS. Nr.: 116287-14-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
MEF	IC₅₀	4 μM Compound: 7	Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay	[PMID: 23566315]
MEF	IC₅₀	4 μM Compound: 7	Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay	[PMID: 36332549]
MEF	IC₅₀	4 μM Compound: Lanperisone	Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay	[PMID: 22297109]

Chemical Information

CAS. Nr. 116287-14-0
Molecular Weight 285.30
Formel C₁₅H₁₈F₃NO
SMILES

O=C([C@@H](CN1CCCC1)C)C2=CC=C(C=C2)C(F)(F)F
Synonyms

NK433 free base
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Tian X, et al. Progress of Ferroptosis in Ischemic Stroke and Therapeutic Targets. Cell Mol Neurobiol. 2024 Feb 23;44(1):25. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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