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Laurdan

26 Cited Publications
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Based on 26 publication(s) in Google Scholar

Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).

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  • Reinheit: 99.79%
  • CAS. Nr.: 74515-25-6
  • Formel: C24H35NO
  • Molecular Weight:353.54
  • Speicherung:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Laurdan Chemical Structure
    Laurdan Chemical Structure
  • Experimental Validation Results for Laurdan
  • Experimental Validation Results for Laurdan
  • Experimental Validation Results for Laurdan
  • Experimental Validation Results for Laurdan
  • Experimental Validation Results for Laurdan
CAS. Nr.: 74515-25-6
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  • Laurdan Chemical Structure
    Laurdan Chemical Structure
    1/16
  • 1/16

    Laurdan purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 29:e05436. [Abstract]

    Customer Validation
     Quantification of membrane fluidity (Laurdan, 2 µM; 24 h) in SiHa cells exposed for 24 h to 15 µm ACOX1i (or DMSO as vehicle); Generalized polarization (GP) was calculated for ER membrane thanks to 1 µM ER-tracker red staining.

  • 1/16

    Laurdan purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Jul 22;44(7):115987. [Abstract]

    Customer Validation
     Laurdan (10 μM). Membrane fluidity of parental, evolved, gene-deletion, and complementation strains treated with 8 μg/mL nitrofurantoin for 1 h.

  • 1/16

    Laurdan purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Aug 13:e2402693. [Abstract]

    Customer Validation
     Representative flow cytometry plots of Annexin V and PI in wild-type (WT) and TMEM16F KO RMA cells after Listeria (Lm) infection, with histograms of Laurdan (30 min) dye fluorescence intensity showing designated gating regions.

  • 1/16

    Laurdan purchased from MedChemExpress. Usage Cited in: J Oral Microbiol. 2023 Dec 10.

    Customer Validation
     Laurdan (10 μM; 30min) staining followed by the calculation of GP to represent cell membrane fluidity.

  • 1/16

    Laurdan purchased from MedChemExpress. Usage Cited in: Cell Mol Life Sci. 2022 Oct 16;79(11):552. [Abstract]

    Customer Validation
     Bacterial cell membrane disruption by Laurdan probe staining. The fuorescence intensity of Laurdan (10 μM; 10 min) was recorded using a microplate reader with excitation at 350 nm and emission at 435 nm and 490 nm.

  • Laurdan