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Art. -Nr.: HY-W123007

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LC-SMCC

Name: LC-SMCC
Brand: MedChemExpress
SKU: HY-W123007
Price: 130.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate))

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LC-SMCC (Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate)) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Reinheit : 98.0%
CAS. Nr.: 125559-00-4
Formel: C₂₂H₂₉N₃O₇
Molecular Weight:447.48

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

LC-SMCC Chemical Structure

CAS. Nr.: 125559-00-4

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

LC-SMCC (Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate)) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

Alle ADC Linkers Isoform-spezifische Produkte anzeigen :

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 125559-00-4
Appearance Solid
Molecular Weight 447.48
Formel C₂₂H₂₉N₃O₇
Color White to off-white
SMILES

O=C(CC1)N(OC(CCCCCNC(C2CCC(CN(C(C=C3)=O)C3=O)CC2)=O)=O)C1=O
Synonyms

Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate)
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 2.5 mg/mL (5.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.2347 mL

11.1737 mL

22.3474 mL

5 mM

0.4469 mL

2.2347 mL

4.4695 mL

10 mM

---

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Cho IH, et al. Rapid pathogen detection by lateral-flow immunochromatographic assay with gold nanoparticle-assisted enzyme signal amplification. Int J Food Microbiol. 2015 Aug 3;206:60-6. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.2347 mL	11.1737 mL	22.3474 mL	55.8684 mL
DMSO	5 mM	0.4469 mL	2.2347 mL	4.4695 mL	11.1737 mL

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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