LY550410
LY550410 is a small-molecule ATP-competitive inhibitor against type I TGF-β receptor kinase, which contains heteroaryl rings for potent binding to the kinase-domain active site. LY550410 modulates TGF-β signalling, thereby regulates gene expression and ultimately cell growth. LY550410 is promising for research of cancers.
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- CAS. Nr.: 737791-20-7
- Formel: C20H16N4
- Molecular Weight:312.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
51 μM
Compound: 3
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Inhibitory activity tested in NIH 3T3 cells
Inhibitory activity tested in NIH 3T3 cells
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[PMID: 15177480] |
Chemical Information
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CAS. Nr. 737791-20-7
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Molecular Weight 312.37
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Formel C20H16N4
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SMILES
C12=C(C3=C4N(CCC4)N=C3C5=CC=CC=N5)C=CN=C1C=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
LY550410 Related Classifications
HY-W684904 Related Classifications
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