MAC glucuronide linker-1
Based on 1 Customer Validation
MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 96.36%
- CAS. Nr.: 2222981-71-5
- Formel: C42H47N3O17S
- Molecular Weight:897.90
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Speicherung:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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Glycosidase Cleavable Linker |
Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 2222981-71-5
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Appearance Solid
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Molecular Weight 897.90
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Formel C42H47N3O17S
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Color White to off-white
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SMILES
O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(COC(NCCS(=O)(C)=O)=O)C=C2NC(CN(C(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (111.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (249 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1137 mL | 5.5685 mL | 11.1371 mL | 27.8427 mL |
| 5 mM | 0.2227 mL | 1.1137 mL | 2.2274 mL | 5.5685 mL | |
| 10 mM | 0.1114 mL | 0.5569 mL | 1.1137 mL | 2.7843 mL | |
| 15 mM | 0.0742 mL | 0.3712 mL | 0.7425 mL | 1.8562 mL | |
| 20 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3921 mL | |
| 25 mM | 0.0445 mL | 0.2227 mL | 0.4455 mL | 1.1137 mL | |
| 30 mM | 0.0371 mL | 0.1856 mL | 0.3712 mL | 0.9281 mL | |
| 40 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6961 mL | |
| 50 mM | 0.0223 mL | 0.1114 mL | 0.2227 mL | 0.5569 mL | |
| 60 mM | 0.0186 mL | 0.0928 mL | 0.1856 mL | 0.4640 mL | |
| 80 mM | 0.0139 mL | 0.0696 mL | 0.1392 mL | 0.3480 mL | |
| 100 mM | 0.0111 mL | 0.0557 mL | 0.1114 mL | 0.2784 mL |
MAC glucuronide linker-1 Related Classifications
HY-44221 Related Classifications
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