(-)-Codonopsine
(-)-Codonopsine is an alkaloid with antibacterial activity. (-)-Codonopsine can be used in research related to Staphylococcus aureus and Escherichia coli infections.
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- CAS. Nr.: 26989-20-8
- Formel: C14H21NO4
- Molecular Weight:267.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
(-)-Codonopsine (0.5-1024 μg/mL; 18 h) inhibits Staphylococcus aureus (ATCC 29213) with a MIC of 32 μg/mL, Escherichia coli (ATCC 25922) with a MIC of 64 μg/mL[1].
(-)-Codonopsine (0.5-1024 μg/mL; 18 h) shows no activity (MIC >1024 μg/mL) against Klebsiella pneumoniae (ATCC 700603), Proteus mirabilis (ATCC 14153), Pseudomonas aeruginosa (ATCC 27853), Acinetobacter baumannii (clinical isolate), and Candida albicans (ATCC 10231)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 26989-20-8
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Molecular Weight 267.32
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Formel C14H21NO4
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SMILES
O[C@@H]1[C@H](N([C@@H]([C@H]1O)C)C)C2=CC(OC)=C(C=C2)OC
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. El-Nezhawy AOH, et al. Design and total synthesis of (-)-codonopsinine, (-)-codonopsine and codonopsinine analogues by O-(2-oxopyrrolidin-5-yl)trichloroacetimidate as amidoalkylating agent with improved antimicrobial activity via solid lipid nanoparticle formulations. Bioorg Med Chem. 2019;27(7):1263-1273. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(-)-Codonopsine Related Classifications
HY-N11554 Related Classifications
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- (-)-Codonopsine
- 26989-20-8
- Bacterial
- Proteus mirabilis (ATCC 14153)
- Staphylococcus aureus (ATCC 29213)
- solid lipid nanoparticle formulations
- Candida albicans
- bacterial infection
- Codonopsis clematidea
- Staphylococcus aureus
- Escherichia coli (ATCC 25922)
- Klebsiella pneumoniae (ATCC 700603)
- central nervous system
- Inhibitor
- inhibitor
- inhibit