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Art. -Nr.: HY-163450

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Nimbiol

Nimbiol exhibits binding energy for FtsZ and shows potential anti-FtsZ effect.

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CAS. Nr.: 561-95-5
Formel: C₁₈H₂₄O₂
Molecular Weight:272.38

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Nimbiol Chemical Structure

CAS. Nr.: 561-95-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Nimbiol exhibits binding energy for FtsZ and shows potential anti-FtsZ effect^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	8.1 μM Compound: 10	Cytotoxicity against human HeLa cells in lag phase of growth after 48 hrs Cytotoxicity against human HeLa cells in lag phase of growth after 48 hrs	[PMID: 24709561]
HeLa	IC₅₀	8.1 μM Compound: 10	Cytotoxicity against human HeLa cells in log phase of growth after 48 hrs Cytotoxicity against human HeLa cells in log phase of growth after 48 hrs	[PMID: 24709561]
HEp-2	IC₅₀	16.2 μM Compound: 10	Cytotoxicity against human Hep2 cells in log phase of growth after 48 hrs Cytotoxicity against human Hep2 cells in log phase of growth after 48 hrs	[PMID: 24709561]
HEp-2	IC₅₀	57.4 μM Compound: 10	Cytotoxicity against human Hep2 cells in lag phase of growth after 48 hrs Cytotoxicity against human Hep2 cells in lag phase of growth after 48 hrs	[PMID: 24709561]
Vero	IC₅₀	14.1 μM Compound: 10	Cytotoxicity against African green monkey Vero cells in lag phase of growth after 48 hrs Cytotoxicity against African green monkey Vero cells in lag phase of growth after 48 hrs	[PMID: 24709561]
Vero	IC₅₀	60.3 μM Compound: 10	Cytotoxicity against African green monkey Vero cells in log phase of growth after 48 hrs Cytotoxicity against African green monkey Vero cells in log phase of growth after 48 hrs	[PMID: 24709561]

Chemical Information

CAS. Nr. 561-95-5
Molecular Weight 272.38
Formel C₁₈H₂₄O₂
SMILES

C[C@@]12C3=CC(O)=C(C)C=C3C(C[C@@]1([H])C(C)(CCC2)C)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Mauricio E Orozco-Ugarriza, et al. Antimicrobial phytoconstituents from Azadirachta indica (neem) with potential inhibitor against FtsZ protein of Pseudomonas aeruginosa. Nat Prod Res. 2024 Mar 22:1-6. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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