Odorine
Odorine (Roxburghiline) is a natural product isolated from branches and leaves of Aglaia odorata. Odorine has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer.
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- CAS. Nr.: 72755-20-5
- Formel: C18H24N2O2
- Molecular Weight:300.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human A431 cells
Cytotoxicity against human A431 cells
|
[PMID: 8496701] |
| HT-1080 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 8496701] |
| KB | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 8496701] |
| KB-V1 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against vinblastine-resistant human KBV1 cells
Cytotoxicity against vinblastine-resistant human KBV1 cells
|
[PMID: 8496701] |
| KB-V1 | ED50 |
6.4 μg/mL
Compound: 3
|
Cytotoxicity against vinblastine-resistant human KBV1 cells by dose-response study in presence of 1 ug/ml vinblastine
Cytotoxicity against vinblastine-resistant human KBV1 cells by dose-response study in presence of 1 ug/ml vinblastine
|
[PMID: 8496701] |
| LNCaP | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 8496701] |
| SK-MEL-2 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
|
[PMID: 8496701] |
| ZR-75-1 | ED50 |
>20 μg/mL
Compound: 3
|
Cytotoxicity against human ZR-75-1 cells
Cytotoxicity against human ZR-75-1 cells
|
[PMID: 8496701] |
Chemical Information
-
CAS. Nr. 72755-20-5
-
Molecular Weight 300.40
-
Formel C18H24N2O2
-
SMILES
CC[C@H](C)C(N[C@@H]1N(CCC1)C(/C=C/C2=CC=CC=C2)=O)=O
-
Synonyms
Roxburghiline
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)