PB01
PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively inhibits high glucose-induced ROS production and mitochondrial superoxide formation while significantly reducing cellular DPP-4 expression. PB01 can also significantly lower blood glucose levels in diabetic mice. Additionally, PB01 demonstrates good safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds potential for research in the field of diabetes.
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- CAS. Nr.: 368434-78-0
- Formel: C18H21N5O3
- Molecular Weight:355.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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DPP-4 15.66 nM (IC50) |
Chemical Information
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CAS. Nr. 368434-78-0
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Molecular Weight 355.39
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Formel C18H21N5O3
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SMILES
O=C1C2=C(N(C)C(N1C)=O)N=C(N3CCOCC3)N2CC4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PB01 Related Classifications
HY-170572 Related Classifications
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