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Art. -Nr.: HY-128844

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Bis-NH2-C1-PEG3

Name: Bis-NH2-C1-PEG3
Brand: MedChemExpress
SKU: HY-128844
Price: 26.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: PROTAC Linker 24)

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Based on 1 Customer Validation

Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.96%
CAS. Nr.: 4246-51-9
Formel: C₁₀H₂₄N₂O₃
Molecular Weight:220.31

Speicherung:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Bis-NH2-C1-PEG3 Chemical Structure

CAS. Nr.: 4246-51-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target^[1]

PEGs

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 4246-51-9
Appearance Liquid (Density: 1.0110 g/cm³)
Molecular Weight 220.31
Formel C₁₀H₂₄N₂O₃
Color Colorless to light yellow
SMILES

NCCCOCCOCCOCCCN
Synonyms

PROTAC Linker 24
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Bis-NH2-C1-PEG3

Bis-NH2-PEG2

Methacrylic acid N-hydroxysuccinimide ester

Benzophenonetetracarboxylic dianhydride

NH2-PEG3-C2-NH-Boc

N3-PEG3-CH2COOH

trans-Cyclohexane-1,2-diol

Amino-PEG3-C2-Azido

N-(2-Hydroxyethyl)acrylamide

2-Methacryloyloxyethyl phosphorylcholine

Biotin-PEG2-Mal

Azido-PEG4-alcohol

2,5-Dioxopyrrolidin-1-yl acrylate

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

Bis-NH2-C1-PEG3

Bis-NH2-PEG2

Methacrylic acid N-hydroxysuccinimide ester

Benzophenonetetracarboxylic dianhydride

NH2-PEG3-C2-NH-Boc

N3-PEG3-CH2COOH

trans-Cyclohexane-1,2-diol

Amino-PEG3-C2-Azido

N-(2-Hydroxyethyl)acrylamide

2-Methacryloyloxyethyl phosphorylcholine

Biotin-PEG2-Mal

Azido-PEG4-alcohol

2,5-Dioxopyrrolidin-1-yl acrylate

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bis-NH2-C1-PEG3 Related Classifications

HY-128844 Related Classifications

Bioz