Rexaceract
Rexaceract (Rexaceractum) is a heteroaryl compound that binds to β-glucocerebrosidase. Rexaceract maintains the conformational stability of β-glucocerebrosidase and exhibits activating activity. Rexaceract can be used in the research of nervous system-related diseases such as neurodegenerative diseases with Parkinsonism, epilepsy, and schizophrenia.
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- CAS. Nr.: 2648407-86-5
- Formel: C21H19FN4O
- Molecular Weight:362.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Rexaceract (Example 71) (6-50 μM; 4-day incubation) binds allosterically to β-glucocerebrosidase in human fibroblasts carrying the L444P mutation, increasing the enzyme activity by 1.2- to 1.7-fold[1].\n
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2648407-86-5
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Molecular Weight 362.40
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Formel C21H19FN4O
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SMILES
O=C(C1=NC(NC2=C(F)C=CC=C2)=CC(N)=C1)NC3CC4=C(C3)C=CC=C4
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Synonyms
Rexaceractum
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Rexaceract Related Classifications
HY-184093 Related Classifications
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