country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-14751S

Copy Link Print Information

Rolapitant-d₄

Name: Rolapitant-d4
Brand: MedChemExpress
SKU: HY-14751S
Availability: PreOrder

(Synonyms: SCH619734-d₄)

Rolapitant-d₄ (SCH619734-d₄) is the deuterated-labeled Rolapitant (HY-14751). Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₅H₂₂D₄F₆N₂O₂
Molecular Weight:504.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Rolapitant-d₄ Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Neurokinin Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 552292-08-7
Molecular Weight 504.50
Formel C₂₅H₂₂D₄F₆N₂O₂
SMILES

FC(F)(F)C1=CC(C(F)(F)F)=CC(C(C([2H])([2H])[2H])([2H])OC[C@]2(C3=CC=CC=C3)CC[C@]4(NC(CC4)=O)CN2)=C1
Synonyms

SCH619734-d₄
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.