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Art. -Nr.: HY-180334

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S-312

S-312 is a calcium antagonist with a bicyclic dihydrothienopyridine structure. S-312 can relax the helical strips of various isolated rabbit arteries procontracted with high potassium depolarizaiton. S-312 competitively imhibits calcium-induced contractions in depolarized basilar and femoral arteries. S-312 increases AV nodal conduction time in Langenedorff-perfused isolated rabbit hearts. S-312 exhibits vasculoselectivity, particularly for cerebral vessel.

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CAS. Nr.: 120004-07-1
Formel: C₂₀H₂₂N₂O₄S
Molecular Weight:386.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

S-312 Chemical Structure

CAS. Nr.: 120004-07-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Alle Calcium Channel Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 120004-07-1
Molecular Weight 386.46
Formel C₂₀H₂₂N₂O₄S
SMILES

O=C(C1=C(C)NC2=C(C1C3=CC([N+]([O-])=O)=CC=C3)C(CC(C)C)=CS2)OC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ninomiya M, et al., Effects of S-312, a new calcium antagonist, on the mechanical and electrophysiological responses of isolated cardiovascular preparations. Jpn J Pharmacol. 1989 Oct;51(2):227-38. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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S-312

Alle Calcium Channel Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

S-312 Related Classifications

HY-180334 Related Classifications