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Art. -Nr.: HY-N1257

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Sculponeatin B

Sculponeatin B is a diterpenoid compound from the plant of the genus Rabdosia, Labiatae.

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CAS. Nr.: 85287-60-1
Formel: C₂₀H₂₄O₆
Molecular Weight:360.40

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Sculponeatin B Chemical Structure

CAS. Nr.: 85287-60-1

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Sculponeatin B is a diterpenoid compound from the plant of the genus Rabdosia, Labiatae^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	1.9 μM Compound: 12	Cytotoxicity against human A549 cells after 48 hrs Cytotoxicity against human A549 cells after 48 hrs	[PMID: 19697926]
A549	IC₅₀	17.1 μM Compound: 11	Cytotoxicity against human A549 cells after 48 hrs by MTS assay Cytotoxicity against human A549 cells after 48 hrs by MTS assay	[PMID: 24219809]
HepG2	IC₅₀	1.77 μM Compound: 12	Cytotoxicity against human HepG2 cells after 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs	[PMID: 19697926]
HL-60	IC₅₀	12.7 μM Compound: 11	Cytotoxicity against human HL60 cells after 48 hrs by MTS assay Cytotoxicity against human HL60 cells after 48 hrs by MTS assay	[PMID: 24219809]
K562	IC₅₀	1.62 μM Compound: 12	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 19697926]
MCF7	IC₅₀	15 μM Compound: 11	Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay	[PMID: 24219809]
RAW264.7	IC₅₀	9.1 μM Compound: 11	Inhibition of LPS-stimulated NO production in mouse RAW264.7 cells after 18 hrs by Griess assay Inhibition of LPS-stimulated NO production in mouse RAW264.7 cells after 18 hrs by Griess assay	[PMID: 24219809]
SMMC-7721	IC₅₀	15.2 μM Compound: 11	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay	[PMID: 24219809]
SW480	IC₅₀	3.5 μM Compound: 11	Cytotoxicity against human SW480 cells after 48 hrs by MTS assay Cytotoxicity against human SW480 cells after 48 hrs by MTS assay	[PMID: 24219809]

Chemical Information

CAS. Nr. 85287-60-1
Molecular Weight 360.40
Formel C₂₀H₂₄O₆
SMILES

O[C@H]1[C@@]([C@]2(C(C3=C)=O)C[C@@]3([H])C1)([H])[C@]4([C@@](CC5)([H])OC2=O)[C@]([C@@]56C)([H])[C@](OC6)([H])OC4
Initial Source
- Plants
- Labiatae
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Fujita T, et al. Cytotoxic and antitumor activities of Rabdosia diterpenoids. Planta Med. 1988;54(5):414-417. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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