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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Art. -Nr.: HY-175552
Target:
Forschungsgebiete:
Art. -Nr.: HY-B0754
CAS. Nr.: 14459-29-1
Synonyms: Hematoporphyrin IX
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Target:
Forschungsgebiete:
Dimethadione (Standard) is the analytical standard of Dimethadione. This product is intended for research and analytical applications. Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal[1].
Art. -Nr.: HY-N1427R
CAS. Nr.: 16409-34-0
Synonyms: Sodium glycyldeoxycholate (Standard)
Category:
Art. -Nr.: HY-W013816
CAS. Nr.: 131-18-0
Forschungsgebiete:
Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant .
Art. -Nr.: HY-100426A
CAS. Nr.: 137275-80-0
Synonyms: MKC242
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Osemozotan hydrochloride (MKC242) is a selective 5-HT1A receptor agonist. Osemozotan hydrochloride decreases the number of c-Fos-positive cells caused by MAMP in mice. Osemozotan hydrochloride can be used for the research of depressive disorder .
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NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning .
Art. -Nr.: HY-114813
CAS. Nr.: 1497249-95-2
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KHG26693 is a thiazole derivative with anti-inflammatory and antioxidant properties. KHG26693 normalizes disturbed glucose metabolism by enhancing glucose utilization and decreasing liver glucose production via insulin release. KHG26693 is promising for research of diabetes .
Art. -Nr.: HY-119064
CAS. Nr.: 85493-98-7
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Forschungsgebiete:
L-645164 is a potent inhibitor of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase. L-645164 produces substantial decreases in circulating serum cholesterol concentrations in dogs. L-645164 is promising for research of central nervous system disorders .
Art. -Nr.: HY-122464B
CAS. Nr.: 62653-85-4
Synonyms: 2-iso Jasmonic acid; 7-iso Jasmonic acid
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7-epi Jasmonic acid is the isomer of (±)-Jasmonic acid (HY-122464). (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
Synonyms: Leucovorin calcium (Standard); Calcium folinate (Standard)
Art. -Nr.: HY-147371
CAS. Nr.: 115618-99-0
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Forschungsgebiete:
Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrP S c levels - .
Art. -Nr.: HY-148610
CAS. Nr.: 893739-96-3
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LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1) .
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AEP-IN-2 is an asparagine endopeptidase (AEP) inhibitor via block AEP cleavage of APP and Tau. AEP-IN-2 has oral activity and decreases Aβ40 and Aβ42 and p-Tau levels .
Art. -Nr.: HY-155716
CAS. Nr.: 2702262-15-3
Forschungsgebiete:
G43-C3-TEG is a glycosyl-transferase inhibitor. G43-C3-TEG reduces the biofilm formation by decreasing the production of EPS (extracellular polysaccharides) .
Art. -Nr.: HY-161883
CAS. Nr.: 3036530-41-0
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JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARCA2 in MV-4-11 cells at 1-10 μM .
Art. -Nr.: HY-180910
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Forschungsgebiete:
SARS-CoV-2 Mpro-IN-53 (Compound 7) is a SARS-CoV-2 M pro inhibitor. SARS-CoV-2 Mpro-IN-53 causes a decrease in M pro radius of gyration .
Art. -Nr.: HY-183138
CAS. Nr.: 86408-45-9
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Forschungsgebiete:
N-Demethyldiltiazem is a metabolite of Diltiazem (HY-B0632). N-Demethyldiltiazem increases coronary blood flow, modulates cardiac function, decreases systemic blood pressure and heart rate, and alters papillary muscle developed tension .
Synonyms: Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate
Category:
Natural Products Plant Neurological Disease Zygophyllaceae Extract Guaiacum officinale L. Extract Other Families Extract Disease Research Fields Inflammation/Immunology
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Target:
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Erythrityl tetranitrate (Tetranitrate; Nitroerythrite), a nitrate ester, is a long-acting vasodilator with properties similar to nitroglycerin. Erythrityl tetranitrate decreases the counter load of the heart and improvement of the pump function of left ventricle in an acute experiment in case of chronic cardiac insufficiency with stasis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
