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Art. -Nr.: HY-164536

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SLCB050

SLCB050 is a compound that blocks the interaction between DX2 and p14/ARF and has anticancer activity. SLCB050 reduces the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner and induces apoptosis and senescence.

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CAS. Nr.: 1848971-16-3
Formel: C₂₁H₁₈O₆
Molecular Weight:366.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SLCB050 Chemical Structure

CAS. Nr.: 1848971-16-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
NSCLC	GI₅₀	>50 μM Compound: SLCB050	Growth inhibition of human NSCLC Growth inhibition of human NSCLC	[PMID: 32208684]
SCLC	GI₅₀	5 μM Compound: SLCB050	Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay	[PMID: 32208684]

Chemical Information

CAS. Nr. 1848971-16-3
Molecular Weight 366.36
Formel C₂₁H₁₈O₆
SMILES

CC1(OC2=CC(OC(C=C3)=O)=C3C=C2C[C@@H]1OC(/C=C/C4=CC=CO4)=O)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ah-Young, et al. "Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression." Cancer Research 76.16 (2016): 4791-4804. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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