Zankiren
Zankiren (A-72517) is an orally active inhibitor for renin. Zankiren exhibits renal vasodilator effect, through reduction of angiotensin II formation without affecting other vasodilator mechanisms.
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- CAS. Nr.: 138742-43-5
- Formel: C35H55N5O6S2
- Molecular Weight:705.97
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 138742-43-5
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Molecular Weight 705.97
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Formel C35H55N5O6S2
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SMILES
CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC([C@H](CC2=CSC=N2)NC([C@@H](CS(=O)(N3CCN(CC3)C)=O)CC4=CC=CC=C4)=O)=O
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Synonyms
A-72517
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wessale JL, Kleinert HD, Calzadilla SV, Kovar PJ, Rosenberg SH.Effects of renin inhibitor A-72517 on hemodynamics and cardiac function in sodium-depleted dogs.Am J Hypertens. 1993 Jun;6(6 Pt 1):514-21. [Content Brief]
[2]. Fisher ND, et al., Renal vascular responses to renin inhibition with zankiren in men. Clin Pharmacol Ther. 1995 Mar;57(3):342-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Zankiren Related Classifications
HY-12174 Related Classifications
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