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Cat. No.: HY-12059B

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AT7867 hydrochloride

Name: AT7867 hydrochloride
Brand: MedChemExpress
SKU: HY-12059B
Availability: PreOrder

5 Cited Publications

고객리뷰

Based on 5 publication(s) in Google Scholar

AT7867 hydrochloride is a potent and orally active inhibitor of AKT and p70 S6 kinase. AT7867 hydrochloride has anticancer effect.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2624336-89-4
화학식: C₂₀H₂₁Cl₂N₃
분자량:374.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

AT7867 hydrochloride Chemical Structure

CAS No.: 2624336-89-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

AT7867 hydrochloride is a potent and orally active inhibitor of AKT and p70 S6 kinase. AT7867 hydrochloride has anticancer effect^[1].

All Akt Isoforms :

Chemical Information

CAS No. 2624336-89-4
분자량 374.31
화학식 C₂₀H₂₁Cl₂N₃
SMILES

ClC1=CC=C(C=C1)C2(CCNCC2)C3=CC=C(C=C3)C4=CNN=C4.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (5)

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Antioxidants (Basel)

Flavonoid Fisetin Alleviates Ovarian Aging of Laying Chickens by Enhancing Antioxidant Capacity and Glucose Metabolic Homeostasis. [Abstract]

2024 Nov 21;13(12):1432. PMID: 39765761
J Biol Chem

The mTOR inhibitor manassantin B reveals a crucial role of mTORC2 signaling in Epstein-Barr virus reactivation. [Abstract]

2020 May 22;295(21):7431-7441. PMID: 32312752
J Funct Foods

55 (2019) 296-304.
Vet Med Sci

Glucose Transport by Follicle-Stimulating Hormone Is Mediated Through the Akt/FOXO1 Pathway in Ovine Granulosa Cells. [Abstract]

2025 Mar;11(2):e70294. PMID: 40065595
Oncotarget

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML. [Abstract]

2016 May 17;7(20):29131-42. PMID: 27074558

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Grimshaw KM, et al. AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growth. Mol Cancer Ther. 2010 May;9(5):1100-10. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AT7867 hydrochloride

5 Cited Publications

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Chemical Information
Publications (5)
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AT7867 hydrochloride

Publications Citing Use of MedChemExpress (MCE) AT7867 hydrochloride

All Akt Isoforms

Biological Activity

제품 설명

Chemical Information

Publications (5)

순도&문서

References

Calculators

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Bioz

Keywords

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AT7867 hydrochloride

Publications Citing Use of MedChemExpress (MCE) AT7867 hydrochloride

All Akt Isoforms

Biological Activity

제품 설명

Chemical Information

Publications (5)

순도&문서

References

Calculators

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