1. GPCR/G Protein
    Neuronal Signaling
  2. CGRP Receptor
  3. Atogepant

Atogepant  (Synonyms: MK-8031; AGN-241689)

Cat. No.: HY-109022 Purity: 99.90%
COA Handling Instructions

Atogepant (MK-8031) is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.

For research use only. We do not sell to patients.

Atogepant Chemical Structure

Atogepant Chemical Structure

CAS No. : 1374248-81-3

Size Price Stock Quantity
1 mg USD 880 In-stock
Estimated Time of Arrival: December 31
5 mg USD 2150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 3500 In-stock
Estimated Time of Arrival: December 31
25 mg USD 6900 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Atogepant:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Atogepant (MK-8031) is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine[1].

IC50 & Target

CGRP[1]

Clinical Trial
Molecular Weight

603.52

Formula

C29H23F6N5O3

CAS No.
SMILES

O=C1[[email protected]]2(CC3=CC(C(N[[email protected]]4C[[email protected]](C5=C(C(F)=CC=C5F)F)([H])[[email protected]](N(C4=O)CC(F)(F)F)C)=O)=CN=C3C2)C6=CC=CN=C6N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (165.69 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6569 mL 8.2847 mL 16.5695 mL
5 mM 0.3314 mL 1.6569 mL 3.3139 mL
10 mM 0.1657 mL 0.8285 mL 1.6569 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.90%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Product Name:
Atogepant
Cat. No.:
HY-109022
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