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Cat. No.: HY-160245

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QL47R

Name: QL47R
Brand: MedChemExpress
SKU: HY-160245
Price: 495.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Customer Review

Based on 1 Customer Validation

QL47R is an approximately isosteric analogue of QL47 (HY-80003). QL47R dose not inhibit the biochemical kinase activity of BTK at concentrations below 10 μM. QL47R dose not display antiproliferative activity on B-Cell Lymphoma Cell Lines at concentrations of less than 10 μM.

For research use only. We do not sell to patients.

Purity: 99.94%
CAS No.: 1579278-89-9
Formula: C₂₇H₂₃N₅O₂
Molecular Weight:449.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

QL47R Chemical Structure

CAS No.: 1579278-89-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1579278-89-9
Appearance Solid
Molecular Weight 449.50
Formula C₂₇H₂₃N₅O₂
Color Off-white to light yellow
SMILES

O=C1C=CC2=CN=C3C=CC(C4=CN(C)N=C4)=CC3=C2N1C5=CC=C6C(N(CC6)C(CC)=O)=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (222.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.2247 mL

11.1235 mL

22.2469 mL

5 mM

0.4449 mL

2.2247 mL

4.4494 mL

10 mM

0.2225 mL

1.1123 mL

2.2247 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu H, et al. Discovery of a potent, covalent BTK inhibitor for B-cell lymphoma. ACS Chem Biol. 2014 May 16;9(5):1086-91. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.2247 mL	11.1235 mL	22.2469 mL	55.6174 mL
	5 mM	0.4449 mL	2.2247 mL	4.4494 mL	11.1235 mL
	10 mM	0.2225 mL	1.1123 mL	2.2247 mL	5.5617 mL
	15 mM	0.1483 mL	0.7416 mL	1.4831 mL	3.7078 mL
	20 mM	0.1112 mL	0.5562 mL	1.1123 mL	2.7809 mL
	25 mM	0.0890 mL	0.4449 mL	0.8899 mL	2.2247 mL
	30 mM	0.0742 mL	0.3708 mL	0.7416 mL	1.8539 mL
	40 mM	0.0556 mL	0.2781 mL	0.5562 mL	1.3904 mL
	50 mM	0.0445 mL	0.2225 mL	0.4449 mL	1.1123 mL
	60 mM	0.0371 mL	0.1854 mL	0.3708 mL	0.9270 mL
	80 mM	0.0278 mL	0.1390 mL	0.2781 mL	0.6952 mL
	100 mM	0.0222 mL	0.1112 mL	0.2225 mL	0.5562 mL

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Minimum order quantity

100 mg

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Biological Activity
- Description
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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QL47R

Biological Activity

Description

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

QL47R Related Classifications

HY-160245 Related Classifications

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Keywords

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