B I09 (Standard)
B I09 (Standard) is the analytical standard of B I09 (HY-107400). This product is intended for research and analytical applications. B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
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- CAS No.: 1607803-67-7
- Formule: C16H17NO5
- Masse moléculaire:303.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 1230 nM (IRE-1 RNase)[1].
Chemical Information
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CAS No. 1607803-67-7
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Masse moléculaire 303.31
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Formule C16H17NO5
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SMILES
OC1=CC=C(C2=C(CNCC2)C3=O)C(O3)=C1C4OCCCO4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ranatunga S, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014 May 22;57(10):4289-301. [Content Brief]
[2]. Tang CH, et al. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124(6):2585-98. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B I09 (Standard) Related Classifications
HY-107400R Related Classifications
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